CCSR

Learn about Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses.

Overview

The Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses is a classification system developed by the Agency for Healthcare Research and Quality (AHRQ) — see the official documentation. It groups more than 70,000 ICD-10-CM diagnosis codes into 550+ clinically meaningful categories across 22 body systems.

This allows diagnoses to be organized into two hierarchical levels of CCSR categorization that are easier to interpret, analyze, and visualize — for example, grouping all tumor-related diagnosis codes under a single neoplasms category.

Applications

Metriport enriches FHIR Conditions by including both descriptive CCSR categories and broader body systems, maximizing flexibility for categorization and analytics.

Key Considerations

A single ICD-10-CM code may map to multiple CCSR categories when it represents more than one clinical concept.

Each CCSR code consists of:

• A three-letter prefix representing a body system or condition category (e.g., END for endocrine disorders).
• A three-digit numeric suffix representing a specific category within that body system (e.g., END002 → Diabetes mellitus without complication).

CCSR Body System Categories

Taken from the CCSR User Guide.

Three-character Abbreviation	ICD-10-CM Body System (largely aligned with chapters in the ICD- 10-CM Code Book)
BLD	Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
CIR	Diseases of the circulatory system
DEN	Dental diseases
DIG	Diseases of the digestive system
EAR	Diseases of the ear and mastoid process
END	Endocrine, nutritional, and metabolic diseases
EXT	External causes of morbidity
EYE	Diseases of the eye and adnexa
FAC	Factors influencing health status and contact with health services
GEN	Diseases of the genitourinary system
INF	Certain infectious and parasitic diseases
INJ	Injury, poisoning and certain other consequences of external causes
MAL	Congenital malformations, deformations and chromosomal abnormalities
MBD	Mental, behavioral, and neurodevelopmental disorders
MUS	Diseases of the musculoskeletal system and connective tissue
NEO	Neoplasms
NVS	Diseases of the nervous system
PNL	Certain conditions originating in the perinatal period
PRG	Pregnancy, childbirth, and the puerperium
RSP	Diseases of the respiratory system
SKN	Diseases of the skin and subcutaneous tissue
SYM	Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified

Where can I find it in Metriport’s patient record?

CCSR codes are found in Condition resources under the code.coding array. CCSR body systems are found in Condition resources under the category array.

{
    ...,
    "resourceType": "Condition",
    "code": {
        "text": "Type 2 diabetes mellitus with mild nonproliferative diabetic retinopathy without macular edema, bilateral",
        "coding": [
            {
                "system": "https://hcup-us.ahrq.gov/toolssoftware/ccsr/ccs_refined.jsp",
                "code": "END003",
                "display": "Diabetes mellitus with complication"
            },
            {
                "system": "https://hcup-us.ahrq.gov/toolssoftware/ccsr/ccs_refined.jsp",
                "code": "END005",
                "display": "Diabetes mellitus, Type 2"
            },
            {
                "system": "https://hcup-us.ahrq.gov/toolssoftware/ccsr/ccs_refined.jsp",
                "code": "EYE005",
                "display": "Retinal and vitreous conditions"
            },
            ...
        ]
    },
    "category": [
        {
            "coding": [
                {
                    "system": "https://hcup-us.ahrq.gov/toolssoftware/ccsr/ccs_refined.jsp",
                    "code": "END",
                    "display": "Endocrine, nutritional, and metabolic diseases"
                }
            ],
        },
        {
            "coding": [
                {
                    "system": "https://hcup-us.ahrq.gov/toolssoftware/ccsr/ccs_refined.jsp",
                    "code": "EYE",
                    "display": "Diseases of the eye and adnexa"
                }
            ],
        },
        ...
    ],
    ...
}